Objective functions used as performance metrics for hydrological models: state-of-the-art and critical analysis

ABSTRACT Hydrological models (HMs) can be applied for different purposes, and a key step is model calibration using objective functions (OF) to quantify the agreement between Wild Yam observed and calculated discharges.Fully understanding the OF is important to properly take advantage of model calibration and interpret the results.This study evalua

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Impact of the deep convection of isoprene and other reactive trace species on radicals and ozone in the upper troposphere

Observations of a comprehensive suite of inorganic and organic trace gases, including non-methane hydrocarbons (NMHCs), halogenated organics and oxygenated volatile organic compounds (OVOCs), obtained from the NASA DC-8 over Canada during the ARCTAS aircraft campaign in July 2008 illustrate that convection is important for redistributing both long-

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Hormone replacement therapy in women with cancer and risk of cancer-specific mortality and cardiovascular disease: a protocol for a cohort study from Scotland and Wales

Abstract Background Hormone replacement therapy (HRT) is widely used and has proven benefits for women with menopausal symptoms.An increasing number of women with cancer experience menopausal symptoms but the safety of HRT use in women with cancer is unclear.There are particular concerns that HRT could accelerate cancer progression in women with ca

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